Mixing medication and grapefruit juice isn’t something that jumps to mind as being dangerous, but depending on the drug involved, it can be lethal. Grapefruit contains bergamottin, dihydroxybergamottin, bergapten and bergaptol, chemicals that act as a natural defence mechanism against pests. These chemicals, part of a group of chemicals called furanocoumarins, interfere with an enzyme called CYP3A4 found … Continue reading The grapefruit juice effect